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Use of Nirsevimab against respiratory syncytial virus (RSV) in Infants

RSV is the leading cause of lower respiratory tract infections in infants. Worldwide, acute lower respiratory infections associated with RSV account for about 1.4 million hospitalizations & 27,300 in-hospital deaths among infants under the age of 6 months annually, according to the WHO. Nirsevimab is a long-acting antibody given as a single intramuscular injection at a dose of 50 mg for infants with a body weight of less than 5 kg, and 100 mg for infants weighing at least 5 kg. If approved, nirsevimab will be the only preventative option for the broad newborn and infant population against RSV.

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