A novel saliva test has been shown to detect HPV-associated oropharyngeal squamous cell carcinoma (OPSSC) with high accuracy in a small study. If the results are validated in subsequent studies, the test has the potential to be used as a screening tool in the general population, say the investigators.
In the small study, the NavDx (Naveris) detected tumor-tissue-modified virus DNA (TTMV) in 43 of 46 plasma samples and in 44 of 46 saliva samples. One plasma sample failed quality control measures, one of each sample type had undetectable TTMV, and one of each type was indeterminate.
Source: Medscape