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Monkeypox : Signs, Symptoms & Treatment

Monkeypox is a zoonotic orthopoxvirus.

Usual onset: 5–21 days post-exposure.

Duration: 2 to 4 weeks.

Route: Human-to-human transmission, exposure to infected body fluids or contaminated objects by small droplets through the airborne route.

Symptoms: Fever, headache, muscle pains, shivering, mostly nonitchy blistering rash on face, hands, soles and swollen lymph nodes.

Complications: Secondary infections, eye infection, visual loss, scarring, encephalitis, sepsis, bronchopneumonia.

Types: Central African (Congo Basin), West African

Diagnosis: Testing for viral DNA PCR

Differential diagnosis: Chickenpox, smallpox

Prevention: Smallpox vaccine, hand washing, covering rash, PPE

Treatment: Supportive, antivirals, vaccinia immune globulin

Medication: Tecovirimat

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