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Uses: Quantitative detection of (1-3)-β-D-Glucan (BDG) in serum samples which signifies the presence of invasive fungal infection. It has got both diagnostic and prognostic application.
Method: Spectrophotometry, Semi-Quantitative Colorimetry
Category: Fungal Infections, Mycology
Reference: Less than 59 pg/mL: Negative
60-79 pg/mL: Indeterminate
Greater than or equal to 80 pg/mL: Positive
Pre-test Information: No special preparation required
Specimen Collection: 2 mL (1 mL min.) serum in 1 Red tube (No additive) preferably Glucan free OR 2 mL (1 mL min.) BAL fluid in a sterile screw capped container OR 1 mL (0.5 mL min.) CSF in a sterile screw capped container. Ship refrigerated or frozen.
Storage: Refrigerated
Stability: Stability Room: 2 hrs
Stability Refrigerated: 48 hrs
Stability Frozen: 2 weeks
Report Availability: Same day – 3 days
More Details: It is indicated for presumptive diagnosis of fungal infection ( eg, P. jirovecii, Aspergillus, or Candida) & should be used in conjunction with other diagnostic procedures. This test does not detect certain fungal species such as Cryptococcus, which produce very low levels of (1,3)-beta-D-glucan. This test will not detect the zygomycetes, such as Absidia, Mucor, and Rhizopus, which are not known to produce (1,3)-beta-D-glucan. In addition, the yeast phase of Blastomyces dermatitidis produces little (1,3)-beta-D-glucan and may not be detected by the assay.